Our Pioneering Approach
Rooted in a deep understanding of how the expression of genes is controlled, our approach represents a new and unexploited field for drug discovery and development. Targeted drug discovery to date has focused largely on inhibiting or otherwise changing the function of abnormal genes and proteins. But many more diseases could be treated by controlling the expression of both abnormal and normal genes, turning them on, off, up or down. Until recently, however, scientists have lacked the tools to study the regulatory regions of the genome that control the expression of genes.
We are now at a pivotal point in time where a confluence of scientific and technological advances is bringing into view what was once beyond our reach. Building on the seminal work of our scientific founders, we have built the first platform dedicated to systematically and efficiently analyzing regulatory regions of the genome to identify disease-causing alterations in gene expression and develop medicines to control the expression of genes critical to a given cell.